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A rare case of epidermal inclusion cyst: an unusual complication of ear surgery
The Egyptian Journal of Otolaryngology volume 36, Article number: 2 (2020)
Epidermal inclusion cysts are common tumours of the hand in industrial workers caused by entrapment of epidermal elements within the dermis. They are unusual in the head and neck region more so in the temporal region.
We present a 27-year-old man with a 3-month history of a slow-growing swelling in the left temporal region. He had a history of chronic otitis media and underwent an end-aural tympanomastoid surgery 5 years earlier. Physical examination revealed a 5 × 3 × 2.5 cm cystic globular minimally tender mass in the temporal fossa along with squamous active otitis media with bony erosion of the outer attic wall. High-resolution computed tomography of the left temporal bone revealed otomastoiditis with erosion of the scutum; ossicles were not identified. We hereby describe the diagnostic challenge and the plan of management of this lesion.
Epidermal inclusion cyst must be considered in the differential diagnosis of temporal fossa lesions especially in patients with a prior history of ipsilateral tympanomastoid surgery.
Epidermal inclusion cysts are an extremely rare clinical entity in the head and neck region. These are ectodermal in origin cysts located within subcutaneous tissue, associated with penetrating trauma or surgery. These lesions are often seen with multiple minor occupational traumas in farmers, carpenters and tailors . The implantation of epidermal elements from otological procedures is extremely rare, and very few cases have been reported till date; hence, we present this rare case. “Everything must be taken into account. When the fact does not meet the theory let go the theory.” .
Otitis media is a very common condition seen in developing countries rarely resulting in complications. The differential diagnosis of temporal fossa swelling are usually infective such as lymphadenitis and suppuration mainly otogenic or dental and traumatic aetiology. Soft-tissue lesions are quite rare in this anatomical region, hence presenting a diagnostic challenge especially with a history of otorrhoea and previous ear surgery. Our case is amongst the few cases reported globally of a large epidermoid cyst within the temporal fossa following endaural ear surgery. The relative scarcity of case reports thus emphasises the rarity of this clinical condition.
Otological procedures require various skin incisions as an approach to the middle ear such as Wildey’s postaural incision, Rosen’s endomeatal incision and Lempert’s endaural incision. As with any surgical intervention, these incisions present with the theoretical risk of implantation of skin or ectodermal elements in the subcutaneous tissue; whilst it holds true for all surgical incisions, the endaural incision carries the highest risk for implantation . This risk of implantation of squamous epithelium increases with the surgery for cholesteatoma. There is evidence on the development of epidermal cysts in the middle ear or tympanic membrane presenting as keratin pearls or secondary cholesteatoma; however, literature search reveals sparse reports of epidermal inclusion cysts within the subcutaneous tissue after ear surgery. Overall, there are three sites of preponderance for development of such cysts: the temporal fossa, the parotid region and deeper cysts extending into infratemporal fossa or the parapharyngeal region. Tovi et al. reported two cases of epidermal cysts after otological procedure within the temporal fossa which had an extension into the infratemporal fossa . A novel endoscopic approach was reported by Fontenot et al. for the excision of an epidermoid cyst within the temporal fossa after tympanoplasty . Ulku et al. reported multiple separate masses resulting from epidermal cysts in the temporal and parotid region with peristyloid extension on MRI in a 46-year-old man with history of modified radical mastoidectomy . Such epidermoid cysts have also been reported by Thompson and Bradley, Walshe et al., and Ozcan et al. within the parotid region following ear surgery [7,8,9].
A 27-year-old male presented with a painless swelling in the left temporal region along with ear discharge from 3 months. He had a history of left ear tympanomastoid surgery via endaural incision 5 years back for chronic otitis media; there is no history of intraoperative or immediate postoperative complication. On otomicroscopy, severe retraction of pars flaccida with keratin debris with erosion of ossicles and scutum was revealed. On external examination, a small well-healed endaural scar was seen along with a fluctuant minimally tender swelling in the temporal fossa extending from the preaural area to the retroauricular groove along the superior aspect of the pinna measuring 5 × 3 × 2.5 cm pushing the pinna forward and outward with no signs of acute infection. A high-resolution computed tomography of the left temporal bone revealed otomastoiditis with erosion of the scutum (Fig. 1). There is a large cystic lesion in close relation to the temporal bone located in the temporal fossa deep to the temporalis muscle which was displacing the pinna laterally.
Cytology of the aspirated contents showed numerous keratin lamellae without inflammatory infiltrate. The patient underwent staged treatment; firstly, the epidermal inclusion cyst was excised from a small superiorly based postaural incision. This dermoid was deep to the temporalis muscle, and the fascia over the muscle was deficient in the preaural region as a result of temporalis fascia graft for previous otological procedure. The cyst was dissected, and the fibrous septae adherent to the soft tissue of the incisural scar tissue were divided and excised in toto (Figs. 2 and 3). There was no extension of epithelium into the middle ear or attic. The scutum erosion was smooth with no ragged edges indicating drilling during previous ear surgery; however, no detailed notes could be obtained. The postoperative healing was unremarkable. Histopathology confirmed the findings of cytology as an epidermoid inclusion cyst. We cannot comment on the source of the original epithelium due to lack of adequate surgical details of the previous ear surgery. Intraoperatively, there was dense adhesion between the endaural scar and the cyst with no direct communication between the cyst and the attic or mesotympanum, thus ruling out direct extension of cholesteatoma. However, implantation of the squamous epithelium from cholesteatoma during previous tympanomastoid surgery cannot be ruled out. Thus, in our case, the origin of the epithelium can be the implantation of squamous epithelium via endaural incision or implantation of cholesteatoma during previous ear surgery.
Later, the patient underwent a revision tympanomastoidectomy for the treatment of chronic otitis media squamous active type. The patient has been in constant follow-up and is currently asymptomatic.
In summary, the literature search highlights the fact that in cases with previous middle ear surgery, there is a risk of implantation of squamous epithelium; hence, epidermal inclusion cyst must be considered in the differential diagnosis of temporal fossa lesions especially in patients with a prior history of ipsilateral tympanomastoid surgery. The authors recommend complete excision of these cysts without spilling the contents to prevent recurrence.
Availability of data and materials
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Centenary Hospital Institutional Ethical Committee permission was obtained, and written informed consent was obtained from the patient.
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Written consent was obtained from the patient including the consent to publish clinical images without revealing identity.
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Mogre, D.A., Ahmed, M.D.F. & Banu, T.P. A rare case of epidermal inclusion cyst: an unusual complication of ear surgery. Egypt J Otolaryngol 36, 2 (2020). https://doi.org/10.1186/s43163-020-00002-8
- Epidermal inclusion cyst
- Temporal fossa
- Tympanomastoid surgery