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Sinus involvement in cases of rhinoscleroma: a cause of antibiotic resistance and early recurrence after medical treatment




To investigate the true incidence of sinus infection in cases of rhinoscleroma, and the possible role of reinfection from the sinuses to explain recurrence and resistant to treatment in cases of scleroma.

Materials and methods

Twenty-five patients with histologically proved granular rhinoscleroma were included in this cohort prospective study.

Results and conclusion

More than one-third of the cases of rhinoscleroma in our series were associated with histologically proved sinus lesions, and these sinus-positive lesions were associated with resistance to standard medical treatment and with early recurrence.


  1. Chan TV, Spiegel JH. Klebsiella rhinoscleromatis of the membranous nasal septum. J Laryngol Otol. 2007; 121: 998–1002

    Article  CAS  PubMed  Google Scholar 

  2. Gaafar HA, Gaafar AH, Nour YA. Rhinoscleroma: an updated experience through the last 10 years. Acta OtoLaryngol. 2011; 131: 440–446

    Article  CAS  PubMed  Google Scholar 

  3. Badrawy R, El Shennawy M. Affection of cervical lymph nodes in rhinoscleroma. J Laryngol Otol. 1974; 88: 261–269

    Article  CAS  PubMed  Google Scholar 

  4. Badia L, Lund VJ. A case of rhinoscleroma treated with ciprofloxacin. J Laryngol Otol. 2001; 115: 220–222

    Article  CAS  PubMed  Google Scholar 

  5. Bailhache A, Dehesdin D, François A, Marie JP, Choussy O. Rhinoscleroma of the sinuses. Rhinology. 2008; 46: 338–341

    PubMed  Google Scholar 

  6. Hoffmann EO, Loose LD, Harkin JC. The Mikulicz cell in rhinoscleroma. Light, fluorescent and electron microscopic studies. Am J Pathol. 1973; 73: 47–58

    CAS  PubMed Central  PubMed  Google Scholar 

  7. Abou Seif SG, Baky FA, El Ebrashy F, Gaafar HA. Scleroma of the upper respiratory passages: A CT study. J Laryngol Otol. 1991;105:198–202

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Ahmed Atef.

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There are no conflicts of interest.

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Atef, A., Talaat, N., El Farouk, A. et al. Sinus involvement in cases of rhinoscleroma: a cause of antibiotic resistance and early recurrence after medical treatment. Egypt J Otolaryngol 28, 8–11 (2012).

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  • chronic sinusitis
  • granuloma
  • rhinoscleroma
  • rifampicine