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Comparison between functional outcomes in patients with unilateral vocal fold paralysis undergoing injection laryngoplasty under general anesthesia versus local anesthesia



Injection laryngoplasty (IL) continues to evolve, as new techniques, approaches, and injection materials are continuously being developed. Although it was performed under general anesthesia in the operating room, IL is now increasingly being performed in an office-based setting.


The aim of this study was to compare functional voice outcomes in patients with unilateral vocal fold paralysis undergoing injection laryngoplasty local versus general anesthesia.

Patients and Methods

A prospective interventional study was done to compare functional outcomes and patient satisfaction between group A (15 patients) with unilateral vocal fold paralysis undergoing injection laryngoplasty under local anesthesia, versus group B (15 patients) with unilateral vocal fold paralysis undergoing injection laryngoplasty under general anesthesia, by analyzing total Arabic Voice Handicap Index (VHI) scores and subscale scores preoperatively and post operatively.


All results obtained in this study showed that there was no significant difference for the functional outcomes and patient satisfaction obtained for both groups under study.


In conclusion, IL under local anesthesia gives similar results as general anesthesia regarding functional outcomes and patient satisfaction of voice quality by themselves as well as by using the voice handicap index.


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Corresponding author

Correspondence to Ayatallah R. Sheikhany MD.

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El-Badrawy, A.R., El-Hoshy, H.M., Sheikhany, A.R. et al. Comparison between functional outcomes in patients with unilateral vocal fold paralysis undergoing injection laryngoplasty under general anesthesia versus local anesthesia. Egypt J Otolaryngol 35, 92–102 (2019).

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  • functional outcomes
  • injection laryngoplasty
  • unilateral vocal fold paralysis
  • voice handicap index