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The Egyptian Journal of Otolaryngology
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Unicentric Castleman disease in the paediatric neck: an unusual case of a rare diagnosis

The Egyptian Journal of Otolaryngology volume 35, pages 230–233 (2019)Cite this article

Abstract

We present a rare case of unicentric Castleman disease (CD) in the paediatric neck. A 12-year-old Caucasian girl was referred to us due to a slowly enlarging, painless right-sided neck mass. Our thorough investigative approach identified unicentric CD, with previously undocumented CD-like features occurring simultaneously in a separate lesion from the lymph node group involved in unicentric CD. Recognition of CD in the paediatric patient is essential, despite the condition’s rarity, to ensure adequate diagnostic work-up and management. We discuss features of unicentric CD, current concepts surrounding histology of the two separate variants of unicentric and multicentric CD, and the implications for management.

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Authors and Affiliations

  1. Department of Otolaryngology/Head and Neck Surgery, Freeman Hospital, NE7 7DN, Newcastle upon Tyne, England

    Simon P. Leckenby MBBS MRes, Nicholas Dawe & Steven M. Powell

  2. Department of Paediatric Immunology, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, England

    Mario Abinun

  3. Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, England

    Mario Abinun

Authors
  1. Simon P. Leckenby MBBS MRes
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  2. Nicholas Dawe
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  3. Mario Abinun
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  4. Steven M. Powell
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Corresponding author

Correspondence to Simon P. Leckenby MBBS MRes.

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Leckenby, S.P., Dawe, N., Abinun, M. et al. Unicentric Castleman disease in the paediatric neck: an unusual case of a rare diagnosis. Egypt J Otolaryngol 35, 230–233 (2019). https://doi.org/10.4103/ejo.ejo_105_18

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  • DOI: https://doi.org/10.4103/ejo.ejo_105_18

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