Skip to main content

Current microbiological pattern and role of respiratory syncytial virus infection in children with acute otitis media in South Jeddah

Abstract

Introduction

Otitis media is one of the most commonly encountered pediatric ENT diseases. Antibiotic resistance is increasing partly because of their overuse and largely because of changing microbiological strains leading to the disease. In this study, we aimed to determine the current microbiological pattern of the disease in children.

Participants and methods

Ear discharges of 200 children with acute otitis media between 6 and 14 years of age were microbiologically examined.

Results

Virus-only infection was positive in 13% of patients, 30% were only bacterial (48% of which is Proteus mirabilis), and 57% had combined viral and bacterial infections.

Conclusion

Changing trends in microbiological patterns warrant further researches to achieve better prevention and treatment.

References

  1. 1

    Sung BS, Chonmaitree T, Broemeling LD, Owen MJ, Patel JA, Hedgpeth DC, Howie VM. Association of rhinovirus infection with poor bacteriologic outcome of bacterial-viral otitis media. Clin Infect Dis 1993; 17:38–42.

    Article  CAS  Google Scholar 

  2. 2

    Brandenburg AH, Beek HA, Moll ME, Osterhaus ME, Claas ECJ. G protein variation in respiratory syncytial virus group-A does not correlate with clinical severity. J Clin Microbiol 2000; 38:3849–3852.

    Article  CAS  Google Scholar 

  3. 3

    De Alarcon A, Walsh EE, Carper HT, La Russa JB, Evans BA, Rakes GP, et al. Respiratory syncytial virus among the common causes of otitis media in children. J Pediatr 2001; 138:311–317.

    Article  Google Scholar 

  4. 4

    Doing KM, Jerkofsky MA, Dow EG, Jellison JA. Use of fluorescent-antibody staining of cytocentrifuge-prepared smears in combination with cell culture for direct detection of respiratory viruses. J Clin Microbiol 1998; 36:2112–2114.

    Article  CAS  Google Scholar 

  5. 5

    Chonmaitree T, Heikkinen T. Role of viruses in middle-ear disease. Ann N Y Acad Sci 1997; 830:143–157.

    Article  CAS  Google Scholar 

  6. 6

    Hall WJ, Hall CB, Speers DM. Respiratory syncytial virus infection in adults: clinical, virologic, and serial pulmonary function studies. Ann Intern Med 1978; 88:203–205.

    Article  CAS  Google Scholar 

  7. 7

    Klein BS, Dollete FR, Yolken RH. The role of respiratory syncytial virus and other viral pathogen in acute otitis media. J Pediatr 1999; 101:16–20.

    Article  Google Scholar 

  8. 8

    Philip A, Brunell MD. In a series of studies of children with acute otitis media by the Calreston group by testing middle ear fluids and nasal wash specimens evidence for viral involvement was found in 41%. Pediatrics 2002; 109:826.

    Article  Google Scholar 

  9. 9

    Wiertsema SP, Chidlow GR, Kirkham LA, Corscadden KJ, Mowe EN, Vijayasekaran S, et al. High detection rates of nucleic acids of a wide range of respiratory viruses in the nasopharynx and the middle ear of children with a history of recurrent acute otitis media. J Med Virol 2011; 83:2008–2017.

    Article  CAS  Google Scholar 

  10. 10

    Endimiani A, Luzzaro F, Brigante G, Perilli M, Lombardi G, Amicosante G, et al. Proteus mirabilis bloodstream infections: risk factors and treatment outcome related to the expression of extended-spectrum beta-lactamases. Antimicrob Agents Chemother 2005; 49: 2598–2605.

    Article  CAS  Google Scholar 

  11. 11

    Van Hasselt P, van Kregten E. Treatment of chronic suppurative otitis media with ofloxacin in hydroxypropyl methylcellulose ear drops: a clinical/ bacteriological study in a rural area of Malawi. Int J Pediatr Otorhinolaryngol 2002; 63:49–56.

    Article  Google Scholar 

  12. 12

    Nwabuisi C,, Ologe FE. Pathogenic agents of chronic suppurative otitis media in Ilorin, Nigeria. East Afr Med J 2002; 79:202–205.

    PubMed  CAS  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Sherif K. Mohamed FACS.

Additional information

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

Rights and permissions

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Mohamed, S.K., Hassan, H.G. Current microbiological pattern and role of respiratory syncytial virus infection in children with acute otitis media in South Jeddah. Egypt J Otolaryngol 33, 623–625 (2017). https://doi.org/10.4103/1012-5574.217387

Download citation

Keywords

  • bacterial
  • otitis media
  • viral