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The Egyptian Journal of Otolaryngology
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Role of septoplasty in reducing the incidence of comorbidities associated with elevated levels of mean platelet volume

The Egyptian Journal of Otolaryngology volume 32, pages 156–160 (2016)Cite this article

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Abstract

Aim

The aim of this study was to analyze the effect of septoplasty on mean platelet volume (MPV) levels in patients with marked nasal septal deviation (MNSD).

Setting and design

This is a prospective study that was carried out in a Government Medical College and Hospital.

Materials and methods

A total of 50 patients were selected after proper history and examination.

Statistical analysis

The data entries were entered into SPSS software and the paired t-test was applied.

Results

Data obtained from preoperative and postoperative blood investigation were analyzed and it was statistically proved that, after septoplasty, the MPV was significantly lowered in patients who had MNSD.

Conclusion

Septoplasty plays an important role in reducing the MPV value in cases with MNSD, and thus other comorbid conditions can be prevented by performing septoplasty in these patients.

References

  1. Murray JAM, Maran AG, Mackenzie IJ, Raab G, Open versus closed reduction of the fractured nose. Arch Otolaryngol 1984; 110: 797–802.

    Article  CAS  Google Scholar 

  2. McKenzie M. Manual of diseases of the nose and the throat. London, UK: Churchill; 1880.

    Google Scholar 

  3. Dubin MR, Pletcher SD. Postoperative packing after septoplasty: is it necessary? Otolaryngol Clin North Am 2009; 42: 279–285.

    Article  Google Scholar 

  4. Liu S, Ren J, Han G, Wang G, Gu G, Xia Q, Li J. Mean platelet volume: a controversial marker of disease activity in Crohn’s disease. Eur J Med Res 2012; 17: 27.

    Article  CAS  Google Scholar 

  5. Drager LF, Polotsky VY, Lorenzi-Filho G. Obstructive sleep apnea: an emerging risk factor for atherosclerosis. Chest 2011; 140: 534–542.

    Article  Google Scholar 

  6. Pizzuli L, Yang A, Martin JF, Lüderitz B Changes in platelet size and count in instable angina pectoris compared to stable or non-cardiac chest pain. Eur Heart J 1998; 19: 80–84.

    Article  Google Scholar 

  7. Ross DW, Ayscue LH, Watson J, Bentley SA. Stability of hematologic parameters in healthy subjects. Intraindividual versus interindividual variation. Am J Clin Pathol 1988; 90: 262–267.

    Article  CAS  Google Scholar 

  8. McNicholas WT. Chronic obstructive pulmonary disease and obstructive sleep apnea: overlaps in pathophysiology, systemic inflammation, and cardiovascular disease. Am J Respir Crit Care Med 2009; 180: 692–700.

    Article  CAS  Google Scholar 

  9. Karpatkin S, Strick N. Heterogeneity of human platelets. V. Differences in glycolytic and related enzymes with possible relation to platelet age. J Clin Invest 1972; 51: 1235–1243.

    Article  CAS  Google Scholar 

  10. Jakubowski JA, Thompson CB, Vaillancourt R, Valeri CR, Deykin D. Arachidonic acid metabolism by platelets of differing size. Br J Haematol 1983; 53: 503–511.

    Article  CAS  Google Scholar 

  11. Sagit M, Korkmaz F, Kavugudurmaz M, Somdas MA Impact of septoplasty on mean platelet volume levels in patients with marked nasal septal deviation. J Craniofac Surg 2012; 23: 974–976.

    Article  Google Scholar 

  12. Poorey VK, Thakur P. Effect of deviated nasal septum on mean platelet volume: a prospective study. Indian J Otolaryngol Head Neck Surg 2014; 66: 437–440

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of ENT, Jawaharlal Nehru Medical College and Hospital (JNMCH), Aligarh Muslim University, Aligarh, Uttar Pradesh, India

    Abdur Rahman MS, Shahab F. Hashmi & Syed A. Hasan

  2. Department of Pathology, Jawaharlal Nehru Medical College and Hospital (JNMCH), Aligarh Muslim University, Aligarh, Uttar Pradesh, India

    Sayeedul H. Arif

Authors
  1. Abdur Rahman MS
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  2. Shahab F. Hashmi
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  3. Syed A. Hasan
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  4. Sayeedul H. Arif
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Corresponding author

Correspondence to Abdur Rahman MS.

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There are no conflicts of interest.

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Rahman, A., Hashmi, S.F., Hasan, S.A. et al. Role of septoplasty in reducing the incidence of comorbidities associated with elevated levels of mean platelet volume. Egypt J Otolaryngol 32, 156–160 (2016). https://doi.org/10.4103/1012-5574.186542

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  • DOI: https://doi.org/10.4103/1012-5574.186542

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