Skip to main content

Role of septoplasty in reducing the incidence of comorbidities associated with elevated levels of mean platelet volume

En

Abstract

Aim

The aim of this study was to analyze the effect of septoplasty on mean platelet volume (MPV) levels in patients with marked nasal septal deviation (MNSD).

Setting and design

This is a prospective study that was carried out in a Government Medical College and Hospital.

Materials and methods

A total of 50 patients were selected after proper history and examination.

Statistical analysis

The data entries were entered into SPSS software and the paired t-test was applied.

Results

Data obtained from preoperative and postoperative blood investigation were analyzed and it was statistically proved that, after septoplasty, the MPV was significantly lowered in patients who had MNSD.

Conclusion

Septoplasty plays an important role in reducing the MPV value in cases with MNSD, and thus other comorbid conditions can be prevented by performing septoplasty in these patients.

References

  1. 1

    Murray JAM, Maran AG, Mackenzie IJ, Raab G, Open versus closed reduction of the fractured nose. Arch Otolaryngol 1984; 110: 797–802.

    CAS  Article  Google Scholar 

  2. 2

    McKenzie M. Manual of diseases of the nose and the throat. London, UK: Churchill; 1880.

    Google Scholar 

  3. 3

    Dubin MR, Pletcher SD. Postoperative packing after septoplasty: is it necessary? Otolaryngol Clin North Am 2009; 42: 279–285.

    Article  Google Scholar 

  4. 4

    Liu S, Ren J, Han G, Wang G, Gu G, Xia Q, Li J. Mean platelet volume: a controversial marker of disease activity in Crohn’s disease. Eur J Med Res 2012; 17: 27.

    CAS  Article  Google Scholar 

  5. 5

    Drager LF, Polotsky VY, Lorenzi-Filho G. Obstructive sleep apnea: an emerging risk factor for atherosclerosis. Chest 2011; 140: 534–542.

    Article  Google Scholar 

  6. 6

    Pizzuli L, Yang A, Martin JF, Lüderitz B Changes in platelet size and count in instable angina pectoris compared to stable or non-cardiac chest pain. Eur Heart J 1998; 19: 80–84.

    Article  Google Scholar 

  7. 7

    Ross DW, Ayscue LH, Watson J, Bentley SA. Stability of hematologic parameters in healthy subjects. Intraindividual versus interindividual variation. Am J Clin Pathol 1988; 90: 262–267.

    CAS  Article  Google Scholar 

  8. 8

    McNicholas WT. Chronic obstructive pulmonary disease and obstructive sleep apnea: overlaps in pathophysiology, systemic inflammation, and cardiovascular disease. Am J Respir Crit Care Med 2009; 180: 692–700.

    CAS  Article  Google Scholar 

  9. 9

    Karpatkin S, Strick N. Heterogeneity of human platelets. V. Differences in glycolytic and related enzymes with possible relation to platelet age. J Clin Invest 1972; 51: 1235–1243.

    CAS  Article  Google Scholar 

  10. 10

    Jakubowski JA, Thompson CB, Vaillancourt R, Valeri CR, Deykin D. Arachidonic acid metabolism by platelets of differing size. Br J Haematol 1983; 53: 503–511.

    CAS  Article  Google Scholar 

  11. 11

    Sagit M, Korkmaz F, Kavugudurmaz M, Somdas MA Impact of septoplasty on mean platelet volume levels in patients with marked nasal septal deviation. J Craniofac Surg 2012; 23: 974–976.

    Article  Google Scholar 

  12. 12

    Poorey VK, Thakur P. Effect of deviated nasal septum on mean platelet volume: a prospective study. Indian J Otolaryngol Head Neck Surg 2014; 66: 437–440

    Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Abdur Rahman MS.

Additional information

Conflicts of interest

There are no conflicts of interest.

Rights and permissions

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work noncommercially, as long as the author is credited and the new creations are licensed under the identical terms.

To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Rahman, A., Hashmi, S.F., Hasan, S.A. et al. Role of septoplasty in reducing the incidence of comorbidities associated with elevated levels of mean platelet volume. Egypt J Otolaryngol 32, 156–160 (2016). https://doi.org/10.4103/1012-5574.186542

Download citation

Keywords

  • mean platelet volume
  • nasal septal deviation
  • septoplasty