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A clinicopathological study of masses arising from sinonasal tract and nasopharynx in north Bengal population with special reference to neoplasms

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Abstract

Introduction

Various masses arise from sinonasal tract and nasopharynx, which are embryologically distinct.

Aims and objectives

A cross-sectional study for 1 year in a tertiary care hospital was carried out.

Materials and methods

Either incisional biopsy or surgical excision sample with proper history and imaging was collaborated.

Results

The total percentage of these tumors during the 1-year period was 3.52%. A total of four nonspecific lesions, 49 non-neoplastic masses, 17 benign neoplastic masses, and 24 malignant neoplastic masses were found.

Conclusion

Non-neoplastic masses were the majority in number (52.12%). Among the neoplastic masses (43.61%), malignant neoplasms constituted 25.53%, a vast majority being nasopharyngeal carcinomas. Immunohistochemistry further helped to differentiate undifferentiated carcinomas into epithelial and lymphoid malignancies.

References

  1. 1

    Wenig BM, Pilch BZ. Tumors of the upper respiratory tract Part A. In: Fletcher CDM, ed. Diagnostic histopathology of tumors. 2nd ed. Churchill Livingstone; 2005. 87–138.

  2. 2

    Rosai J. Rosai and Ackerman’s surgical pathology. 9th ed. New York: Mosby; 2004. 305–334.

    Google Scholar 

  3. 3

    Balogh K. Mouth, nose, and paranasal sinuses. Histology of Pathologists 1997; 2: 367–390.

    Google Scholar 

  4. 4

    Walike JW. Anatomy of the nasal cavities. Otolaryngol Clin North Am 1973; 6: 609–621.

    CAS  Article  Google Scholar 

  5. 5

    Vander Coer JM, Marres HA, Wielinga EW, Wong-Alcala LS. Rhinosporidiosis in Europe. J Laryngol Otol 1992; 106:440–443.

    Article  Google Scholar 

  6. 6

    Wolff M. Granulomas in nasal mucoid membranes following local steroid injections. Am J Clin Pathol 1974; 62: 775–782.

    CAS  Article  Google Scholar 

  7. 7

    Heffner DK. Problems in paediatric otorhininolaryngic pathology. Sinonasal and nasopharyngeal tumors and masses with myxoid features. Int J Pediatr Otorhinolaryngol 1983; 5: 77–91.

    CAS  Article  Google Scholar 

  8. 8

    Wenig BM, Heffner DK. Respiratory epithelial adenomatoid hamartomas of the sinonasal tract and nasopharynx: a clinicopathologic study of 31 cases. Ann Otol Rhinol Laryngol 1995; 104: 639–645.

    CAS  Article  Google Scholar 

  9. 9

    Friedman I, Osborn DA. Tumors of the nose and paranasal sinuses — material and classification. In: Pathology of the granulomas and neoplasms of the nose and paranasal sinuses. Edinburg: Churchill Livingstone; 1982. 100–102.

    Google Scholar 

  10. 10

    Panchal L, Vaideeswar P, Kathpal D, Madiwale CV, Prabhat DP. Sinonasal epithelial tumors: a pathological study of 69 cases. J Postgrad Med 2005; 51: 30–35.

    CAS  PubMed  Google Scholar 

  11. 11

    Arber DA, Weiss LM, Albújar PF, Chen Yuan-Yuan BS, Jaffe ES. Nasal lymphomas in Peru: high incidence of T-cell immunophenotype and EBV infection. Am J Surg Pathol 1993; 17:392–399.

    CAS  Article  Google Scholar 

  12. 12

    Abbondanzo SL, Wenig BM. Non Hodgkin’s lymphoma of the sinonasal tract — a clinicopathologic and immunophenotypic study of 120 cases. Cancer 1995; 75: 1281–1291.

    CAS  Article  Google Scholar 

  13. 13

    ICMR Bulletin. Epidemiological and etiological factors associated with nasopharyngeal carcinoma. 2003; 33:0377–4910.

    Google Scholar 

  14. 14

    Calderon-Garciduenas L, Delgado R, Calderon-Garciduenas A, Meneses A, Ruiz LM, De La Garza J, et al. Malignant neoplasms of the nasal cavity and paranasal sinuses: a series of 256 patients in Mexico City and Monterrey. Is air pollution the missing link?. Otolaryngol Head Neck Surg 2000; 12:499–508.

    Google Scholar 

  15. 15

    Mills SE, Fechner RE. The nose, paranasal sinuses, and nasopharynx. In: Sternberg SS, ed. Diagnostic surgical pathology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 1999. 885–892.

    Google Scholar 

  16. 16

    Zafar U, Khan N, Afroz N, Hasan SA. Clinicopathological study of non-neoplastic lesions of nasal cavity and paranasal sinuses. Indian J Pathol Microbiol 2008; 51: 26–29.

    CAS  Article  Google Scholar 

  17. 17

    Dasgupta A, Ghosh RN, Mukherjee C. Nasal polyps — histopathologic spectrum. Indian J Otolaryngol Head Neck Surg 1997; 49: 32–36.

    CAS  PubMed  PubMed Central  Google Scholar 

  18. 18

    Tondon PL, Gulati J, Mehta N. Histological study of polypoidal lesions in the nasal cavity. Indian J Otolaryngol 1971; 13: 3–11.

    Google Scholar 

  19. 19

    Samaddar RR, Sen MK. Rhinosporidiosis in Bankura. Indian J Pathol Microbiol 1990; 33: 129–136.

    CAS  PubMed  Google Scholar 

  20. 20

    Chopra H, Dua K, Malhotra V, Gupta RP, Puri H Invasive fungal sinusitis of isolated sphenoid sinus in immunocompetent subjects. Mycoses 2006; 49: 30–36.

    Article  Google Scholar 

  21. 21

    Challa S, Uppin SG, Hanumanthu S, Panigrahi MK, Purohit AK, Sattaluri S, et al. Fungal rhinosinusitis: a clinicopathological study from South India. Eur Arch Otorhinolaryngol 2010; 267: 1239–1245.

    Article  Google Scholar 

  22. 22

    Tsai TL, Ho CY, Guo YC, et al. Fibrous dysplasia of the ethmoid sinus. J Chin Med Assoc 2003; 66: 192.

    Google Scholar 

  23. 23

    Frierson HF, Mills SE, Fechner RE, Taxy JB, Levine PA. Sinonasal undifferentiated carcinoma: an aggressive neoplasm derived from schneiderian epithelium and distinct from olfactory neuroblastoma. Am J Surg Pathol 1986; 10: 771–772.

    Article  Google Scholar 

  24. 24

    Buchwald C, Franzman MB, Tos M. Sinonasal papillomas: a report of 82 cases in Copenhagen County including a longitudinal epidemiological and clinical study. Laryngoscope 1995; 105: 72–79.

    CAS  Article  Google Scholar 

  25. 25

    Manning JT, Batsakis JG. Salivary-type neoplasms of the sinonasal tract. Ann Otol Rhinol Laryngol 1991; 100: 691–694.

    CAS  Article  Google Scholar 

  26. 26

    Kumar S, Dutta LP. Dietary risk factors. Curr Sci 1991; 61: 445.

    Google Scholar 

  27. 27

    Kumar S, Zinyu R, Singh IKK, Medhi SB, Baruah T, Das B, Dutta LP. Studies on nasopharyngeal carcinoma with reference to the North Eastern Region of India. Ann Natl Acad Med Sci (India) 1996; 32: 199–208.

    Google Scholar 

  28. 28

    Zinyu R, Kumar S, Dutta LP. Studies on cancer of the nasopharynx in Nagaland, India. T Sacriston, et al., ed. Proceedings of the XVI World Congress of otorinolaryngology and head and neck surgery. Amesterdam: Kuglar and Ghedini Pubications; 1990. 1279.

    Google Scholar 

  29. 29

    Y-L Ye, M-H Zhou, X-Y Lu, Y-R Dai, W-X Wu. Nasopharyngeal and nasal malignant lymphoma: a clinicopathological study of 54 cases. Histopathology 1992; 20:511–516.

    CAS  Article  Google Scholar 

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Correspondence to Ranjan Bhattacharyya MD,DNB (Psychiatry).

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Bhattacharya, J., Goswami, B.K., Banerjee, A. et al. A clinicopathological study of masses arising from sinonasal tract and nasopharynx in north Bengal population with special reference to neoplasms. Egypt J Otolaryngol 31, 98–104 (2015). https://doi.org/10.4103/1012-5574.156091

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Keywords

  • Clinicopathological study
  • Mass
  • Sinonasal tract
  • Nasopharynx