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Diagnosis and management of benign tumors of nasal and paranasal cavities: 31 cases




To precise the clinical, paraclinical and therapeutic features of the benign tumors of nasal and paranasal cavities.


We report a retrospective study carried out in the ENT Department of the Military Hospital of Tunis, Tunisia over a period of 10 years (2003-2012).


We report 31 patients operated for benign tumors of the nasal and paranasal cavities. The mean age was 38 years (2 months to 73 years), and the sex ratio was 2.4 (22 male and nine female). The diagnosis was assessed through endoscopic and radiological findings. Surgery was underwent by an endonasal approach in 84% and an external approach in 16% of the cases. The evolution after surgery was different according to the histological type of the tumor.


Benign tumors of the nasal and paranasal cavities are characterized by their histological diversity. Thus, clinical presentation is variable and nonspecific. Their diagnosis has been improved by modern imaging techniques and is definitely confirmed after histological examinations. Actually, endoscopic surgery of the paranasal sinuses has become the procedure of choice for treatment.


  1. Bonfils P. Benign tumors of the nose and sinuses: the inverted papilloma. EMC Otorhinolaryngol 2007; 2: 1–15 [Article 20-400-A-10].

    Google Scholar 

  2. Dym R, Masri D, Shifteh K. Imaging of the paranasal sinuses. Oral Maxillofacial Surg Clin N 2012; 24: 175–189.

    Article  Google Scholar 

  3. Lawson W, Patel ZM. The evolution of management for inverted papilloma: an analysis of 200 cases. Otolaryngol Head Neck Surg 2009; 140: 330–335.

    Article  Google Scholar 

  4. Tomenzoli D, Castelnuovo P, Pagella F, Berlucchi M, Pianta L, Delù G, et al. Different endoscopic surgical strategies in the management of inverted papilloma of the sinonasal tract: experience with 47 patients. Laryngoscope 2004; 114:193–200.

    Article  Google Scholar 

  5. Dhanapala N, Ravis Hanker C, Ramya B, Supriya B. A rare case of sinonasal cavernous hemangioma. Res Otolaryngol 2013; 2: 12–14.

    Google Scholar 

  6. Vorasubin N, Vira D, Suh JD, Bhuta S, Wang MB. Schneiderian papillomas: comparative review of exophytic, oncocytic, and inverted types. Am J Rhinol Allergy 2013; 27: 287–292.

    Article  Google Scholar 

  7. Wassef SN, Batra PS, Barnett S. Skull base inverted papilloma: a comprehensive review. ISRN Surg 2012; 2012: 175903.

    Article  Google Scholar 

  8. Buchwald C, Franzmann MB, Jacobsen GK, Lindeberg H. The presence of human papillomavirus in sinonasal papillomas, demonstrated by polymerase chain reaction with consensus primers. Hum Pathol 1993; 24: 1354–1356.

    Article  CAS  Google Scholar 

  9. Krouse JH. Development of a staging system for inverted papilloma. Laryngoscope 2000; 110: 965–968.

    Article  CAS  Google Scholar 

  10. Bacon CK, Hendrix RA. Inverted papillomas of the nasal septum. Trans Pa Acad Ophthalmol Otolaryngol 1990; 42: 1008–1013.

    CAS  PubMed  Google Scholar 

  11. Yoon JH, Kim CH, Choi EC. Treatment outcomes of primary and recurrent inverted papilloma: an analysis of 96 cases. J Laryngol Otol 2002; 116: 699–702.

    Article  Google Scholar 

  12. Nachtigal D, Yoskovitch A, Frenkiel S, Braverman I, Rochon L. Unique characteristics of malignant schneiderian papilloma. Otolaryngol Head Neck Surg 1999; 121: 766–771.

    Article  CAS  Google Scholar 

  13. Vargas MC, Castillo M. Sinonasal cavernous haemangioma: a case report. Dentomaxillofac Radiol 2012; 41: 340–341.

    Article  CAS  Google Scholar 

  14. Kumar Gupta D, Somavanshi S, Agrawal A, Bharti R, Shree N. Capillary hemangioma of the lateral nasal wall. Int J 2012; 5:127–129.

    Google Scholar 

  15. Hamdan AL, Kahwaji G, Mahfoud L, Husseini S. Cavernous hemagioma of the maxillary sinus: a rare cause of epistaxis. Middle East J Anaesthesiol 2012; 21: 757–760.

    PubMed  Google Scholar 

  16. Sinha A, Jha D, Deka RC. Osteoma of the paranasal sinuses. Indian J Otolaryngol Head Neck Surg 2013; 55: 166–169.

    Google Scholar 

  17. Mansour AM, Salti H, Uwaydat S, Dakroub R, Bashshour Z. Ethmoid sinus osteoma presenting as epiphora and orbital cellulitis: case report and literature review. Surv Ophthalmol 1999; 43: 413–426.

    Article  CAS  Google Scholar 

  18. Pierse JE, Stern A. Benign cysts and tumors of the paranasal sinuses. Oral Maxillofac Surg Clin North Am 2012; 24: 249–264.

    Article  Google Scholar 

  19. Verma RK, Kalsotra G, Vaiphei K, Panda NK. Large central osteoma of maxillary sinus: a case report. Egypt J Ear Nose Throat Allied Sci 2012; 13: 65–69.

    Article  Google Scholar 

  20. Dubey SP, Murthy DP, Kaleh LK, Vele DD. Malignant tumours of the nasal cavity and the paranasal sinuses in a Melanesian population. Auris Nasus Larynx 1999; 26: 57–64.

    Article  CAS  Google Scholar 

  21. Jégoux F, Métreau A, Louvel G, Bedfert C. Paranasal sinus cancer. Eur Ann Otorhinolaryngol Head Neck Dis 2013; 130: 327–335.

    Article  Google Scholar 

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Correspondence to Mardassi Ali MD.

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Ali, M., Nabil, M., Safa, N. et al. Diagnosis and management of benign tumors of nasal and paranasal cavities: 31 cases. Egypt J Otolaryngol 31, 4–9 (2015).

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