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The Egyptian Journal of Otolaryngology
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Topical tranexamic acid versus hot saline for field quality during endoscopic sinus surgery

The Egyptian Journal of Otolaryngology volume 30, pages 327–331 (2014)Cite this article

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Abstract

Objectives

This study conducted to evaluate and compare between topical tranexamic acid (TA) and hot saline as an alternative to local vasoconstrictors on bleeding and surgery site quality during endoscopic sinus surgery (FESS).

Patients and methods

This study was performed on 75 patients with class I and II American society of anesthesiologists (A.S.A.), scheduled for elective FESS under general anesthesia. Patients divided into three groups, each (25 patients), group A: topical tranexamic acid (1000mg diluted in 20ml normal saline) was used during surgery for packing and irrigation, group B: hot saline up to 50°C was used and group C:(control group) normal saline was used.

Results

The use of local (TA) was associated with significant decrease in estimated blood loss 214.2 ml more than local hot saline which was 216.75 and both is much better than the normal saline which was 272.66. Also (TA) and hot saline showed decrease in the duration of surgery, improve the surgical field quality and blinded surgeon satisfaction as compared with the control group.

Conclusion

The use of local TA and local hot saline up to 50°C achieved reduction in blood loss, duration of surgery and improved surgical field quality during FESS.

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Authors and Affiliations

  1. Department of Otorhinolaryngology, Faculty of Medicine, Benha University, Benha, Egypt, 13515

    Ahmed Shehata MD

  2. Anesthesia and ICU Department, Faculty of Medicine, Benha University, Benha, Egypt

    Mohammed Sabra Ibrahim & Mohammed Hamed Abd-El-Fattah

Authors
  1. Ahmed Shehata MD
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  2. Mohammed Sabra Ibrahim
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  3. Mohammed Hamed Abd-El-Fattah
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Corresponding author

Correspondence to Ahmed Shehata MD.

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None declared.

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Shehata, A., Ibrahim, M.S. & Abd-El-Fattah, M.H. Topical tranexamic acid versus hot saline for field quality during endoscopic sinus surgery. Egypt J Otolaryngol 30, 327–331 (2014). https://doi.org/10.4103/1012-5574.144965

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