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Serial histopathological tracheal changes from prolonged intubations
The Egyptian Journal of Otolaryngology volume 30, pages 142–146 (2014)
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Abstract
Introduction
Prolonged tracheal intubations are usually complicated by subglottic stenosis. The aim of this study was to identify the pathological changes in the trachea due to prolonged endotracheal intubations.
Materials and methods
A prospective study was conducted on 35 patients who were admitted to the ICUs for different periods of time and tracheostomy operation was planned for them. The part of the trachea that was removed during tracheostomy was examined histopathologically.
Results
The most common histopathological finding was inflammation and ulceration. Fibrosis was also found with evidence of cartilage necrosis. All histopathological findings were more prevalent among patients who were intubated for 1 week.
Conclusion
Prolonged endotracheal intubations are associated with various histopathological changes ranging from erosion of the epithelium to necrosis of the cartilage and fibrosis.
Level of evidence
Level 2b.
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Badr El Din, M.H., Ahmed, M.R., Hinnis, A.R. et al. Serial histopathological tracheal changes from prolonged intubations. Egypt J Otolaryngol 30, 142–146 (2014). https://doi.org/10.4103/1012-5574.133218
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DOI: https://doi.org/10.4103/1012-5574.133218