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Table 2 A summary of complications following clival chordoma surgery reported in literature

From: Endoscopic endonasal approach for skull base chordoma

Author(s), year

Patients

GTR

Major complications

Jho and Ha. [25], 2004

3

100%

CSF leak, PE, AF, and Stroke (33%)

Solares et al. [26], 2005

3

66.7%

Frank et al. [27], 2006

9

33%

ICA injury (11%)

Hwang and Ho. [28], 2007

3

100%

Carrabba et al. [29], 2008

60

59%

Hematoma, hemiparesis, and hydrocephalus (6%)

CSF leak (24%)

Tension pneumocephalus (6%)

Zhang et al. [30], 2008

7

85%

Subarachnoid hemorrhage (14%)

Dehdashti et al. [31], 2008

12

58%

Hemiparesis (8%)

CSF leak (33%)

Hong et al. [11], 2009

9

66.7%

Stippler et al. [32], 2009

20

45%

ICA injury (5%)

Brainstem hemorrhage, quadriparesis, and lower cranial neuropathy (5%)

Holzmann et al. [33], 2010

13

92%

Tan et al. [34], 2012

14

50%

Basilar artery injury (7%)

Hydrocephalus (7%)

Pneumocephalus (7%)

CSF leak (21%)

Satio et al. [5], 2012

6

50%

Hydrocephaluls and brain stem infarction (16%)

Ouyang et al. [35], 2014

77

32.5%

Cerebral infarction (3.2%)

Lower cranial nerve palsy (4.8%)

CSF leak (4.8%)