Fig. 6From: Ectopic upper third molar embedded in a dentigerous cyst of the maxillary sinus: a case report and literature reviewAn immunohistochemical study shows: A S100-positive Langerhans cell numbers in the lining epithelial and subepithelial connective tissues confirmed the association of high-grade inflammation and thick lining epithelium with the increased Langerhans cell number in a dentigerous cyst. B CD68 expression in Langerhans cells was present in defense mechanisms with the release of pro-inflammatory cytokines, which is responsible for inducing the continued proliferation of cystic epithelium. C CD1a-positive Langerhans cell numbers in the lining epithelial and subepithelial connective tissues confirmed the association of inflammation and thick lining epithelium with the increased Langerhans cell number in a dentigerous cyst (magnification × 10)Back to article page