Total thyroidectomy versus subtotal thyroidectomy in treatment of multinodular goiter: a meta-analysis

The Egyptian Journal of Otolaryngology

Table 9 Meta-analysis of the incidence of recurrence

Study	Total thyroidectomy	Subtotal thyroidectomy	Relative risk	95% CI	z	p value
Barczynski et al. 2010 [3]	1/200	22/200	0.05	0.006 to 0.33
Pappalardo et al. 1998 [5]	0/69	10/72	0.05	0.003 to 0.83
Tezelman et al. 2009 [7]	0/1211	121/1695	0.006	0.0004 to 0.09
Vaiman et al. 2008 [8]	0/3834	482/2238	0.0006	0.00004 to 0.001
Yang et al. 2009 [4]	0/165	12/181	0.04	0.003 to 0.74
Total (fixed effects)	1/5479	647/4386	0.004	0.001 to 0.01	− 10.594	< 0.001
Total (random effects)	1/5479	647/4386	0.013	0.002 to 0.11	− 3.954	< 0.001
Test for heterogeneity
Q	13.484
DF	4
p value	0.009
I² (inconsistency)	70.34%
95% CI for I²	24.44 to 88.35