Table 1 Major and minor criteria for diagnosis of GGS [6, 7]
From: A rare case report of Gorlin-Goltz’s syndrome: a multisystemic disorder of otolaryngological domain
Major criteria | Minor criteria |
|---|---|
• Multiple basal cell carcinomas or one occurring under the age of 20 years • Multiple OKCs of the jaws • Palmar pits or plantar pits (three or more) • Calcifications in the falx cerebri • Bifid, fuséd, or markedly splayed ribs • First-degree relative with nevoid basal cell carcinoma syndrome | • Macrocéphaly (adjusted for height) • Congenital malformation: cléft lip or cleft palate, frontal bossing, coarse face, moderate or severe hypertelorism • Other skeletal abnormalities: Spréngel deformity, marked pectus deformity, marked syndáctyly of the digits • Radiological abnormalities: bulging of sélla turcica, vertebral anomalies such as hemivertebrae, fusion or elongation of vertebral bodies, modeling defects of the hands and feet, or flame-shaped hands or feet • Ovarian fibroma • Medulloblastoma |