Table 2 Subgroup analysis of E-cad expression pattern in oral squamous cell carcinoma with respect to clinicopathological predictors
Variable | Groups (n) | Membrane expression of E-cad | Mean rank | Chi-square statistic | Kruskal–Wallis (p value) | Proportional odds regression | |||
|---|---|---|---|---|---|---|---|---|---|
0 | 1 + | 2 + | 3 + | ||||||
Sub-site | Oral tongue (25) | 3 | 2 | 14 | 6 | 20.18 | 8.267 | 0.041 | NA a |
Buccal mucosa (13) | 0 | 0 | 9 | 4 | 32.54 | ||||
Alveolus (8) | 1 | 0 | 4 | 3 | 23.94 | ||||
RMT (2) | 0 | 0 | 1 | 1 | 28.50 | ||||
Differentiation | G1 (32) | 1 | 1 | 14 | 16 | 27.63 | 5.779 | 0.016 | 0.007 |
G2 + G3 (16) | 3 | 1 | 9 | 3 | 18.25 | ||||
T Stage | T1 (6) | 2 | 0 | 2 | 2 | 19.83 | 2.113 | 0.549 | 0.212 b |
T2 (15) | 1 | 2 | 7 | 5 | 22.30 | ||||
T3 (14) | 0 | 0 | 8 | 6 | 27.00 | ||||
T4 (13) | 1 | 0 | 6 | 6 | 26.50 | ||||
LN | Positive (21) | 1 | 1 | 10 | 9 | 25.67 | 0.313 | 0.576 | 0.152 |
Negative (27) | 3 | 1 | 13 | 10 | 23.59 | ||||
ENE | Positive (16) | 1 | 1 | 9 | 5 | 22.81 | 0.421 | 0.516 | 0.052 |
Negative (32) | 3 | 1 | 14 | 14 | 25.34 | ||||
LVI | Present (22) | 1 | 1 | 11 | 9 | 25.32 | 0.168 | 0.682 | 0.458 |
Negative (26) | 3 | 1 | 12 | 10 | 23.81 | ||||