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The Egyptian Journal of Otolaryngology

Table 1 Correlation of E-cad expression in tumour with the various clinicopathological predictors

From: E-cadherin expression pattern in head and neck squamous cell carcinoma and its association with clinico-pathological predictors

Variables

Groups (n)

Membrane expression of E-cad

Mean rank

Chi-square statistic

Kruskal–Wallis test (p value)

Proportional odds regression

0

1 + 

2 + 

3 + 

Age (in years)

Below 55 (30)

3

0

10

17

32.87

1.339

0.247

0.557

55 and above (30)

2

2

14

12

28.13

Sex

Male (46)

4

2

16

24

31.33

0.536

0.464

0.817

Female (14)

1

0

8

5

27.79

Site

Oral cavity (48)

4

2

23

19

28.07

5.634

0.018

0.076

Larynx/hypopharynx (12)

1

0

1

10

40.21

Nature of tumour

Primary (51)

5

2

22

22

28.80

3.898

0.048

0.320

Recurrent (9)

0

0

2

7

40.11

Differentiation

G1 (35)

1

1

14

19

33.04

2.165

0.141

0.012

G2 + G3 (25)^

4

1

10

10

26.94

T stage

T1 (6)

2

0

2

2

22.83

6.638

0.084

0.129a

T2 (16)

2

2

7

5

24.09

T3 (16)

0

0

8

8

32.75

T4 (22)

1

0

7

14

35.61

Lymph node

Positive (24)

1

1

11

11

30.42

0.001

0.973

0.083

Negative (36)

4

1

13

18

30.56

ENE

Present (17)

1

1

10

5

25.56

2.308

0.129

0.035

Absent (43)

4

1

14

24

32.45

LVI

Present (31)

1

1

13

16

33.08

1.702

0.192

0.398

Absent (29)

4

1

11

13

27.74

  1. ^As there was only one case of G3, it has been merged with G2 for simplification of statistical analysis
  2. aFor multivariate analysis, tumour stages T1 and T2 were combined to 1 group, and T3 and T4 into another
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