Table 2 Information extracted from included studies

Pandit (2011) [7]

A/J mice

Olfactory stem cells; human; xenogeneic

Direct into cochlea;

ABR

Immune response

4 wks after;

Zhou (2011) [8]

BALB/c mice

Adipose-derived stem cells; human; xenogeneic

Intraperitoneally;

ABR

Immune response

2 wks after;

Choi, B (2012) [9]

Sprague Dawley rat

Bone marrow; human; xenogeneic

Infusion via tail vein;

ABR

Immune response

48–96 h after;

Choi, M (2012) [10]

C57BL/6 J mice

Umbilical cord blood; human; xenogeneic

Infusion via brachial vein;

ABR & DPOE

MSC recovery and survival

3 days after;

Kasagi (2013) [11]

C57BL/6 J mice

Bone marrow; mice; allogenic

into ampulla of the semicircular canal;

ABR

N/A

Not reported;

Yoo (2015) [12]

BALB/c mice

Adipose-derived cells; human; xenogeneic

Intraperitoneally;

ABR

N/A

2 weeks after;

Kil (2016) [13]

Guinea Pig

Placental-derived cells; human; xenogeneic

IV via brachial vein;

ABR & DPOE

MSC recovery and engraftment

3 days after;

Ma (2016) [14]

Pigs

Umbilical cord blood; human; xenogeneic

Into the subarachnoid cavity;

ABR

MSC recovery and engraftment

N/A;

Chen (2018) [15]

CBA/CaJ mice

Limbal cells from corneal transplant; human; xenogeneic

Injection around cochlear nerve;

ABR & DPOE

MSC recovery and engraftment

2 weeks after;