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Table 3 Response-operating characteristic (ROC) curve analysis for discrimination between cases and controls using IL-5 and comparison of the (ROC) curves for discrimination between cases and controls using IL-5 HS or IL-5 AV

From: Role of interleukin-5 in allergic fungal sinusitis: deeper insight

Variable

IL-5 HS

IL-5 AV

Area under the ROC curve (AUC)

0.759

0.814

ΔAUC

0.055

SE for ΔAUC

0.0551

95% CI for ΔAUC

-0.053 to 0.163

Standard Error

0.064

0.050

95% Confidence interval (CI)

0.642 to 0.854

0.704 to 0.897

z statistic

4.032

6.265

p-Value (AUC = 0.5)†

 < .001

 < .001

Youden index J

0.42

0.54

Best cut-off criterion

 > 6.0%

 > 5.0%

Sensitivity

92%

64%

Specificity

50%

90%

z-value

0.999

p-value†

.318

  1. †DeLong method