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Table 2 Clinical and therapeutic features of patients

From: Culture-negative necrotizing otitis externa: diagnosis and management

 

Age/Sex

History

Clinical examination

Complications

Extension

Treatment

Serology

Improvement

Recurrence

1

84/M

DM

Edema and granulations

No

Tympanal bone erosion

Ceftazidime cipro

Negative

Yes

No

2

73/M

DM

Edema and granulations

No

Tympanal bone erosion

Ceftazidime cipro

Negative

Yes

No

3

83/F

DM

Edema and granulations

Facial palsy

Tympanal bone erosion and soft-tissue involvement

First line: Ceftazidime cipro

Second line: Teicoplanin, fusidic acid, imipenem, and voriconazole

Positive (Aspergillus)

Yes

No

4

54/M

DM

Edema and granulations

No

Tympanal bone erosion

CIPRO 15J

Negative

Yes

Yes (after 1 year)

5

65/F

DM

Edema and granulations

No

Tympanal bone erosion

Ceftazidime cipro

Negative

Yes

No

6

53/F

DM

Polyps in the EAC

No

____

Ceftazidime cipro

Negative

Yes

No

7

43/M

DM

Edema and granulations

No

Tympanal bone erosion

First line: Ceftazidime cipro

Second-line: voriconazole

Positive (Aspergillus)

Yes (after second line)

No

8

53/F

UNCT

Polyps in the EAC

No

Tympanal bone erosion

Ceftazidime cipro

Negative

Yes

Yes (after 6 months)

9

50/F

UNCT

Polyps in the EAC

No

High tissue activity at the temporal bone, the mastoid and the skull base

Ceftazidime cipro

Negative

Yes

No

10

60/F

DM

Polyps in the EAC

No

____

Ceftazidime cipro

Negative

Yes

No

11

68/M

DM

Edema and granulations

No

High tissue activity at the temporal bone, the mastoid and the skull base

Imipenem cipro

Negative

Yes

No

12

70/F

DM

Edema and granulations

No

Tympanal bone erosion

Imipenem cipro

negative

Yes

No

13

45/M

DM

Edema and granulations

Facial palsy

Tympanal bone erosion and soft-tissue involvement

First line: Ceftazidime cipro

Second line: Imipenem

negative

Yes after second line

Yes (after 6 monthes)

  1. MD diabetes mellitus, UNCT undifferentiated carcinoma of nasopharyngeal type, cipro ciprofloxacin, M male, F female