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Table 2 Treatment possibilities for cystic lymphangiomas of the tongue [2, 5, 6, 8]

From: Cystic lymphangiomas of the tongue: 3 rare cases and a literature review of classifications and therapeutic possibilities

Treatment mode:

Pitfalls of treatment.

- Surgical excision [2, 5, 8].

Surgical techniques:

- Wedge resection.

- Bilateral marginal resection.

- U-shaped resection.

- Jian or Dignan glossectomy.

- Cryotherapy [2, 5, 8]

Is a minimal invasive therapy option that is primarily indicated in stages I and II lesions. (Li Hisiung et al.) Is used for small locailzed lesions, as it does not seem to affect lesions with extension.

- Electrocautery [2, 3, 8]

Only palliative benefit

- Radiation therapy [2, 3, 5, 8]

Irradiation is no longer used, as it is unable to completely distroy lesions, with the possibility of malignancy induction.

- Sclerotherapy O.K 432 [2, 5, 8]

Is indicated for macrocystic lesions, since sclerosing substance cannot diffuse through cystic lumens.

Can be a good alternative to surgery, with Bleomycin: 0.25–0.6 mg/kg or 0.75-0.8 U/kg with 2 weeks to 2 months intervalle, with a cumulative dose of 30 mg or 150 U, or 5 mg per kg (15 U/kg).

Side effect: pulmonary complications, which is redoutable and related to cumulative dose.

- Embolization [2, 8]

Has been investigated and could be discussed in larges cases.

- Steroid administration. (Usha et al.) (Susanne Wiegand et al.). (Li Hisiung et al.)

Local injection of steroid has been described by Khurana et al.

- Laser surgery [2, 8]

Complete excision with CO2 laser shows advantages of less edema, less trauma to underlying tissues, and less blood loss compared to surgery. Difficulty of excision of microcystic lesions due to the difficulty in diffrentiation between healthy and infiltrated tissue.

- Radio-frequency tissue ablation technique [2, 8]

Is a minimal invasive therapy option that is primarily indicated in stages I and II lesions.