Identification of sequence polymorphisms in the D-loop region of mitochondrial DNA as valuable biomarkers for salivary gland tumors: an observational study

The Egyptian Journal of Otolaryngology

Table 2 Uncommon D-loop variations among the groups

Locus	Base change	Region	PA (N = 5)	MEC (N=6)	ACC (N = 5 )	Total
35	G-A	MT-CR	0 (0%)	0 (0%)	1 (100%)	1
36	G-A	MT-CR	0 (0%)	0 (0%)	1 (100%)	1
143	G-A	HV-II	1 (100%)	0 (0%)	0 (0%)	1
200	A-G	HV-II	1 (100%)	0 (0%)	0 (0%)	1
235	A-G	HV-II	1 (100%)	0 (0%)	0 (0%)	1
482	T-C	HV-II	1 (100%)	0 (0%)	0 (0%)	1
16274	G-A	HV-I	0 (0%)	0 (0%)	1 (100%)	1
16278	C-T	HV-I	0 (0%)	1 (100%)	0 (0%)	1
16290	C-T	HV-I	0 (0%)	0 (0%)	1 (100%)	1
16292	C-T	HV-I	0 (0%)	0 (0%)	1 (100%)	1
16295	C-T	HV-I	1 (100%)	0 (0%)	0 (0%)	1
16456	G-A	Non coding region	0 (0%)	0 (0%)	1 (100%)	1

PA pleomorphic adenoma, MEC mucoepidermoid carcinoma, ACC adenoid cystic carcinoma, PLGA polymorphous low-grade adenocarcinoma, HV hypervariable