Table 2 Demographic and disease characteristics of patients according to PNI status
From: Perineural invasion is a better prognostic factor than extranodal extension in head and neck cancer
PNI- (n: 32,%) | PNI+ (n: 17,%) | p value | |
|---|---|---|---|
Characteristics | |||
Median age, years | |||
< 57 | 16 (50) | 7 (41.2) | 0.55 |
≥ 57 | 16 (50) | 10 (58.8) | |
Gender | 0.69 | ||
Male | 26 (81.3) | 13 (76.5) | |
Female | 6(18.8) | 4 (23.5) | |
T stage | 0.11 | ||
T1-2 | 15 (46.9) | 4 (23.5) | |
T3-4 | 17(53.1) | 13 (76.5) | |
Lymph node metastasis | |||
Yes | 21 (65.6) | 12 (70.6) | 0.72 |
No | 11 (34.4) | 5 (29.4) | |
ENE | 0.06 | ||
Yes | 10 (31.2) | 10 (58.8) | |
No | 22 (68.8) | 7 (41.2) | |
Grade | 0.52 | ||
I | 14 (43.8) | 10 (58.8) | |
II | 10 (31.3) | 3 (17.6) | |
III | 8 (25) | 4 (23.5) | |
LVI | 0.02 | ||
Yes | 7 (21.9) | 9 (52.9) | |
No | 25 (78.1) | 8 (47.1) | |
Surgery margin | |||
Clear | 25 (78.1) | 14 (82.4) | 0.72 |
Positive | 7 (21.9) | 3 (17.6) | |
Adjuvant treatment | |||
Radiotherapy | 3 (9.4) | 3 (17.6) | 0.44 |
Chemoradiotherapy | 21 (65.6) | 12 (70.6) | |
No | 8 (25) | 2 (11.8) | |
Recurrence | 0.27 | ||
Yes | 22 (68.8) | 9 (52.9) | |
No | 10 (31.2) | 8 (47.1) | |