Table 1 Clinicopathological characteristics of all patients
From: Perineural invasion is a better prognostic factor than extranodal extension in head and neck cancer
Variable | n (%) |
|---|---|
Median age, years (range) | 57 (36–82) |
Sex | |
Men | 39 (79.6) |
Women | 10 (20.4%) |
Grade | |
Well differentiated | 24 (49) |
Moderately differentiated | 13 (26.5) |
Poorly differentiated | 12 (24.5) |
Site of tumor | |
Supraglottic larynx | 11 (22.4) |
Glottic larynx | 5 (10.2) |
Subglottic larynx | 8 (16.3) |
Tonsil | 2 (4.1) |
Oral cavity | 2 (4.1) |
Lip | 4 (8.2) |
Tongue | 11 (22.4) |
Paranasal sinus | 2 (4.1) |
Salivary gland | 3 (6.1) |
Hypopharynx | 1 (2) |
LVI | |
Yes | 16 (32.7) |
No | 33 (67.3) |
PNI | |
Yes | 17 (34.7) |
No | 32 (65.3) |
ENE | |
Yes | 20 (40.8) |
No | 19 (59.2) |
Margin status | |
Clear | 39 (79.6) |
Involved by tumor | 10 (20.4) |
Pathological T classification | |
T1 | 2 (4.1) |
T2 | 17 (34.7) |
T3 | 17 (34.7) |
T4a | 13 (26.5) |
Pathological N classification | |
N0 | 16 (32.7) |
N1 | 6 (12.2) |
N2b, N2c | 3 (6.1), 5 (10.2) |
N3b | 19 (38.8) |
Treatment | |
Surgery | 10 (20.4) |
Surgery + radiotherapy | 6 (12.2) |
Surgery + chemoradiotherapy | 33 (67.3) |