Fig. 4
From: Temporal bone rhabdomyosarcoma mimicking otitis media complicated by facial nerve palsy
The figure shows stratified squamous epithelium (red arrow) with an underlying neoplastic growth formed of alternating hypocellular myxoid areas (black arrow) and hypercellular areas (blue arrow) (A, H&E ×100). The neoplastic cells are predominantly primitive small hyperchromatic round and spindled cells (B, H&E, ×400) with few scattered rhabdomyoblasts (white arrow) (C, H&E, ×400). Immunohistochemistry for myogenin (L026, Leica biosystems, USA) shows strong and diffuse nuclear staining of the neoplastic cells (D, ×400)