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Fig. 3 | The Egyptian Journal of Otolaryngology

Fig. 3

From: Localized Erdheim-Chester disease involving the thyroid gland—a case report

Fig. 3

a Histopathology of the Tru-Cut biopsy specimen from the lesion showing fibroadipose tissue infiltrated by the sheets of foamy histiocytes and Touton-type giant cells (arrows) along with lymphoid cells (hematoxylin and eosin stain; original magnification × 400). Immunohistochemistry showing b diffuse positive staining for CD68 (original magnification × 100), c, d negative staining for CD1a and S-100, respectively (original magnification × 100), and e positive staining for BRAFV600E mutation (Ventana platform immunohistochemistry; original magnification × 400)

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