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The Egyptian Journal of Otolaryngology

Table 2 Analysis of the correlation of all variables and the incidence of thyroid gland invasion by the LC

From: Incidence and predictors of thyroid gland invasion by laryngeal carcinoma: a 7-year experience review

 

Thyroid gland invasion

P value*

OR (95% CI)

 

Yes (n = 24)

No (n = 353)

Gender

    

 Male

23 (95.8)

330 (93.5)

0.648

1.6 (0.2-12.4)

 Female

1 (4.2)

23 (6.5)

 

Ref.

Age

    

 < 50

2 (8.3)

42 (11.9)

0.888

Ref.

 50-59

9 (37.5)

122 (34.6)

 

1.5 (0.3-7.5)

 60-69

12 (50)

164 (46.5)

 

1.5 (0.3-7.1)

 70+

1 (4.2)

25 (7.1)

 

0.8 (0.1-9.7)

Histological type

    

 SCC

22 (91.7)

349 (98.9)

0.049

Ref.

 Others

2 (8.3)

4 (1.1)

 

7.9 (1.4-45.4)

Neck dissection

    

 Yes

21 (87.5)

322 (91.2)

0.466

0.7 (0.2-2.4)

 No

3 (12.5)

31 (8.8)

 

Ref.

T staging

    

 T2

1 (4.2)

34 (9.6)

0.004

Ref.

 T3

0 (0)

98 (27.8)

 

0.1 (0.001-2.9)

 T4a

23 (95.8)

221 (62.6)

 

3.5 (0.5-27.1)

T staging

    

 T2 + T3

1 (4.2)

132 (37.4)

0.001

Ref.

 T4a

23 (95.8)

221 (62.6)

 

13.7 (1.8-102.9)

N staging

    

 No

15 (62.5)

219 (62)

0.204

Ref.

 N1

2 (8.3)

54 (15.3)

 

0.5 (0.1-2.4)

 N2a

0 (0)

2 (0.6)

 

2.8 (0.1-61.6)

 N2b

6 (25)

34 (9.6)

 

2.6 (0.9-7.1)

 N2c

1 (4.2)

37 (10.5)

 

0.4 (0.1-3.1)

 N3

0 (0)

7 (2)

 

0.9 (0.1-17.3)

Degree of differentiation

    

 Well differentiation

2 (8.3)

31 (8.8)

0.004

Ref.

 Moderate

18 (75)

311 (88.1)

 

0.9 (0.2-4.0)

 Poor

4 (16.7)

11 (3.1)

 

5.6 (0.9-35.0)

Degree of differentiation

    

 Well + moderate

20 (83.3)

342 (96.9)

0.004

Ref.

 Poor

4 (16.7)

11 (3.1)

 

6.2 (1.8-21.3)

Site of the primary tumor

    

 Supraglottic

0 (0)

27 (7.6)

< 0.001

 

 Glottic

0 (0)

13 (3.7)

  

 Subglottic

1 (4.2)

0 (0)

  

 Glottic supraglottic

4 (16.7)

156 (44.2)

  

 Glottic subglottic

4 (16.7)

78 (22.1)

  

 Glottic, supra, sub

15 (62.5)

79 (22.4)

  

Glottic invasion

    

 Yes

23 (95.8)

326 (92.4)

0.529

1.9 (0.2-14.7)

 No

1 (4.2)

27 (7.6)

 

Ref.

Supraglottic invasion

    

 Yes

19 (79.2)

262 (74.2)

0.590

1.3 (0.5-3.6)

 No

5 (20.8)

91 (25.8)

 

Ref.

Subglottic invasion

    

 Yes

20 (83.3)

157 (44.5)

< 0.001

6.2 (2.1-18.6)

 No

4 (16.7)

196 (55.5)

 

Ref.

Thyroid cartilage invasion

    

 Yes

18 (75)

223 (63.2)

0.243

1.7 (0.7-4.5)

 No

6 (25)

130 (36.8)

 

Ref.

Thyroid cartilage invasion

    

 No

6 (25)

130 (36.8)

0.090

Ref.

 Microscopic

0 (0)

32 (9.1)

 

0.3 (0.02-5.6)

 Gross

18 (75)

191 (54.1)

 

2.0 (0.8-5.3)

Nodal metastasis

    

 Yes

9 (37.5)

134 (38)

0.964

0.98 (0.4-2.3)

 No

15 (62.5)

219 (62)

 

Ref.

Margin invasion

    

 Yes

4 (16.7)

21 (5.9)

0.065

3.2 (0.99-10.1)

 No

20 (83.3)

332 (94.1)

 

Ref.

Hostile pathological features

    

 Yes

2 (8.3)

10 (2.8)

0.174

3.1 (0.6-15.1)

 No

22 (91.7)

343 (97.2)

 

Ref.

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